Mewgenics vs Slay the Spire 2
Mewgenics rewards long-term genetic tinkering; Slay the Spire 2 offers a short, unfinished co-op deckbuilding loop.
Updated 16d ago
Makes good on the decade-long Mewgenics dev cycle — McMillen and Glaiel's cat-genetics roguelite hits Isaac territory at 89 MC and 94% recommend.
Still the best in its genre — the new multiplayer co-op alone justifies the buy even in early access.
By the numbers
Prices checked Oct 8; they move faster than we refresh, so confirm on the store page.
Recent-review figures are Steam's own last-30-days window, read Oct 8.
| Measure | Mewgenics | Slay the Spire 2 |
|---|---|---|
| Value Too close to call | ||
| Price now | $29.99 Steam | $24.99 Steam |
| All-time low | $22.49 | $24.99 |
| Cost / hour | $0.39/hr $29.99 · 76 h main story | $2.61/hr $24.99 · 10 h main story |
| Off its low | +33% low was Jun 2026 | At its low low was Mar 2026 |
| Main story | 76 h | 10 h |
| Health Mewgenics wins on player health | ||
| Steam reviews | 90% 55k reviews | 61% 204k reviews |
| Recent reviews | 87% 1k votes · vs 90% lifetime | 72% 4k votes · vs 61% lifetime · improving |
| Peak players | 6,729 Sep 2026 · ↑ 17% MoM | 101,134 Sep 2026 · ↓ 4% MoM |
| Launch peak | 6% of Feb 2026 launch peak · as of Sep 2026 | 18% of Mar 2026 launch peak · as of Sep 2026 |
| All-time peak | 115,063 Feb 2026 | 574,638 Mar 2026 |
| Support | ||
| Last patch | 5 weeks ago | 8 weeks ago |
| Patch cadence | 5 in last 90 days | 4 in last 90 days |
| Steam Deck | Platinum | Platinum |
Shared scale — same months across the bottom, same player-count axis up the side, so the two lines are directly comparable. A shorter line means a younger game.
What players say
Patterns from long-haul reviewers, taken from each game's verdict. Not live sentiment — each side is dated below.
Mewgenics
The cat-breeding loop's mutation chains and roguelike adventure variety are what 200-hour fans replay for.
The brutality of losing a well-bred cat line is the wall that ends many long playthroughs.
from our May 2026 verdict
Slay the Spire 2
The new four-player co-op hooks even skeptical friends, and regular updates keep the card pool evolving
Ascension 10 balancing draws consistent frustration — brutal enemy scaling and RNG-heavy bosses feel unfair to many
from our August 2026 verdict
Key differences
Which one is for you?
Pick Mewgenics if
- You loved Binding of Isaac and want McMillen's turn-based roguelite pivot
- You enjoy deep meta-progression and don't mind 200+ hour run cycles
- You play on PC only and want a finished game now
Pick Slay the Spire 2 if
- You've sunk hours into the original Slay the Spire and want a fresh card pool
- You prefer co-op deck-building with friends over solo runs
- You're okay with early access and frequent balance changes
Bottom line
If you want a complete, deep roguelite with a 76-hour main story, pick Mewgenics; if you crave co-op deckbuilding now and can tolerate early access, pick Slay the Spire 2.